Make sure you don't have "wavetable" checked when you open the settings dialog (gears icon)
Also, the only solution to prevent crackles with web-only audio is to reduce the canvas score height in the settings dialog (try something like 200px or less, lowering the polyphonic/note lifetime settings can help as well)
Some settings such as show globalTime/show osc infos may also affect the amount of crackles.
Sadly, web-audio only will stay with more than high requirement for some time until some new features of the Web Audio API are released (might come in 2018/2019)
The alternative solution (which work best and make use of your audio interface) is to use the audio server/launcher.